Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. [electronic resource]
Producer: 20010628Description: 999-1010 p. digitalISSN:- 0021-9525
- Animals
- Apoptosis -- drug effects
- Caspase Inhibitors
- Caspases -- metabolism
- Cathepsin B -- antagonists & inhibitors
- Cell Size -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Chromatin -- drug effects
- Cystatins -- pharmacology
- Cytosol -- drug effects
- Enzyme Activation -- drug effects
- Fibroblasts
- Fibrosarcoma -- enzymology
- Genes, Dominant -- genetics
- Lysosomes -- drug effects
- Mice
- NF-kappa B -- metabolism
- Oligonucleotides, Antisense -- genetics
- Phosphatidylserines -- metabolism
- Protein Transport -- drug effects
- Receptors, TNF-Related Apoptosis-Inducing Ligand
- Receptors, Tumor Necrosis Factor -- metabolism
- Signal Transduction -- drug effects
- Transfection
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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