Blockade of CD40 ligand suppresses chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4. [electronic resource]
Producer: 20010816Description: 6893-8 p. digitalISSN:- 0022-1767
- Abatacept
- Animals
- Antibody Specificity
- Antigens, CD
- Antigens, Differentiation -- biosynthesis
- B-Lymphocytes -- immunology
- CD40 Ligand -- immunology
- CTLA-4 Antigen
- Cell Differentiation -- immunology
- Cells, Cultured
- Chronic Disease
- Cytokines -- biosynthesis
- Down-Regulation -- immunology
- Female
- Humans
- Hypersensitivity, Delayed -- immunology
- Immune Sera -- administration & dosage
- Immunoconjugates
- Immunoglobulin G -- biosynthesis
- Immunoglobulin Isotypes -- biosynthesis
- Immunosuppressive Agents -- administration & dosage
- Injections, Intraperitoneal
- Injections, Subcutaneous
- Lymphocyte Activation -- immunology
- Myasthenia Gravis, Autoimmune, Experimental -- immunology
- Rats
- Rats, Inbred Lew
- Receptors, Cholinergic -- administration & dosage
- Th1 Cells -- immunology
- Th2 Cells -- immunology
- Torpedo -- immunology
- Up-Regulation -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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