IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways. [electronic resource]
Producer: 20010614Description: L1094-103 p. digitalISSN:- 1040-0605
- ADP Ribose Transferases
- Actins -- metabolism
- Antibodies -- pharmacology
- Botulinum Toxins
- Cells, Cultured
- Chemokine CXCL1
- Chemokines, CXC
- Chemotactic Factors -- pharmacology
- Cytoskeleton -- drug effects
- Dose-Response Relationship, Drug
- Endothelium, Vascular -- cytology
- Enzyme Inhibitors -- pharmacology
- Growth Substances -- pharmacology
- Humans
- Intercellular Signaling Peptides and Proteins
- Interleukin-8 -- pharmacology
- Intracellular Signaling Peptides and Proteins
- Lung -- blood supply
- Microcirculation -- cytology
- Monomeric GTP-Binding Proteins -- antagonists & inhibitors
- Pertussis Toxin
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Receptors, Interleukin-8A -- antagonists & inhibitors
- Receptors, Interleukin-8B -- antagonists & inhibitors
- Signal Transduction -- physiology
- Stress Fibers -- metabolism
- Virulence Factors, Bordetella -- pharmacology
- cdc42 GTP-Binding Protein -- metabolism
- rac GTP-Binding Proteins -- metabolism
- rho GTP-Binding Proteins -- antagonists & inhibitors
- rho-Associated Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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