Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells. [electronic resource]
Producer: 20010521Description: 1047-55 p. digitalISSN:- 0012-1797
- Animals
- Apoptosis -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Cytokines -- antagonists & inhibitors
- DNA Fragmentation -- drug effects
- Flow Cytometry
- Gene Expression Regulation, Enzymologic -- drug effects
- Genes, Reporter
- Glucose -- pharmacology
- In Vitro Techniques
- Insulin -- metabolism
- Insulin Secretion
- Interferon-gamma -- toxicity
- Interleukin-1 -- toxicity
- Islets of Langerhans -- cytology
- Luciferases -- genetics
- Mice
- NF-kappa B -- genetics
- Nitric Oxide Synthase -- genetics
- Nitric Oxide Synthase Type II
- Rats
- Recombinant Proteins -- metabolism
- Tissue Inhibitor of Metalloproteinase-1 -- genetics
- Tissue Inhibitor of Metalloproteinase-2 -- pharmacology
- Transfection
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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