The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. [electronic resource]
Producer: 20010531Description: 584-90 p. digitalISSN:- 1078-8956
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacokinetics
- Aryl Hydrocarbon Hydroxylases
- Cell Line
- Cytochrome P-450 Enzyme System -- genetics
- Dioxoles -- pharmacology
- Docetaxel
- Gene Expression Regulation -- physiology
- Humans
- Isoquinolines -- pharmacology
- Paclitaxel -- analogs & derivatives
- Pregnane X Receptor
- Receptors, Steroid -- antagonists & inhibitors
- Steroid 16-alpha-Hydroxylase
- Steroid Hydroxylases -- genetics
- Taxoids
- Tetrahydroisoquinolines
- Trabectedin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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