Epstein-Barr Virus and its glycoprotein-350 upregulate IL-6 in human B-lymphocytes via CD21, involving activation of NF-kappaB and different signaling pathways. [electronic resource]
Producer: 20010531Description: 501-14 p. digitalISSN:- 0022-2836
- B-Lymphocytes -- drug effects
- CCAAT-Enhancer-Binding Protein-beta -- metabolism
- Cells, Cultured
- DNA -- genetics
- Enzyme Inhibitors -- pharmacology
- Half-Life
- Herpesvirus 4, Human -- metabolism
- Humans
- Interleukin-6 -- biosynthesis
- Membrane Glycoproteins -- metabolism
- NF-kappa B -- metabolism
- Promoter Regions, Genetic -- genetics
- Protein Binding
- Protein Kinase C -- antagonists & inhibitors
- RNA Stability -- drug effects
- RNA, Messenger -- genetics
- Receptors, Complement 3d -- metabolism
- Receptors, Virus -- metabolism
- Response Elements -- genetics
- Signal Transduction -- drug effects
- Transcriptional Activation -- drug effects
- Transfection
- Up-Regulation -- drug effects
- Viral Matrix Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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