Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)--mediated cytotoxicity by selective up-regulation of TRAIL-R1. [electronic resource]
Producer: 20010614Description: 2596-603 p. digitalISSN:- 0006-4971
- Animals
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Erythroblasts -- drug effects
- Humans
- Leukemia, Erythroblastic, Acute -- pathology
- Membrane Glycoproteins -- pharmacology
- Mice
- Receptors, TNF-Related Apoptosis-Inducing Ligand
- Receptors, Tumor Necrosis Factor -- agonists
- Signal Transduction
- TNF-Related Apoptosis-Inducing Ligand
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- pharmacology
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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