Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. [electronic resource]
Producer: 20010906Description: 191-9 p. digitalISSN:- 1055-9965
- Analysis of Variance
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Cell Division -- drug effects
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p16 -- analysis
- Diet
- Dimethylnitrosamine -- analogs & derivatives
- Disease Models, Animal
- Drug Interactions
- Eflornithine -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Esophageal Neoplasms -- chemically induced
- Genes, bcl-2
- Immunohistochemistry
- Male
- Polyamines -- analysis
- Proliferating Cell Nuclear Antigen
- Proto-Oncogene Proteins -- analysis
- Proto-Oncogene Proteins c-bcl-2
- Rats
- Rats, Sprague-Dawley
- Sensitivity and Specificity
- Zinc -- deficiency
- bcl-2-Associated X Protein
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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