Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. [electronic resource]
Producer: 20010607Description: 104-6 p. digitalISSN:- 0036-8075
- Aging -- physiology
- Alleles
- Animals
- Body Constitution
- Carrier Proteins -- genetics
- Crosses, Genetic
- Drosophila Proteins
- Drosophila melanogaster -- genetics
- Female
- Fertility
- Genes, Insect
- Heterozygote
- Hot Temperature
- Insect Proteins -- genetics
- Insulin -- metabolism
- Insulin Receptor Substrate Proteins
- Intracellular Signaling Peptides and Proteins
- Longevity -- physiology
- Male
- Mutation
- Oxidative Stress
- Protein-Tyrosine Kinases -- genetics
- Receptor Protein-Tyrosine Kinases
- Receptor, Insulin -- metabolism
- Reproduction
- Signal Transduction
- Somatomedins -- metabolism
- Starvation
- Superoxide Dismutase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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