Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism. [electronic resource]
Producer: 20010426Description: 965-78 p. digitalISSN:- 0006-2952
- Animals
- Cartilage -- cytology
- Chondrocytes -- drug effects
- Cyclooxygenase 2
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors -- pharmacology
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Enzymologic -- drug effects
- Indomethacin -- pharmacology
- Interleukin-1 -- metabolism
- Isoenzymes -- antagonists & inhibitors
- Male
- Nitric Oxide Synthase -- antagonists & inhibitors
- Nitric Oxide Synthase Type II
- Nitrites -- metabolism
- Nitrobenzenes -- pharmacology
- Prostaglandin-Endoperoxide Synthases -- genetics
- Proteoglycans -- biosynthesis
- Rats
- Rats, Wistar
- Sulfonamides -- pharmacology
- Thiourea -- pharmacology
- omega-N-Methylarginine -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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