In vivo neutralization of human IL-6 (hIL-6) achieved by immunization of hIL-6-transgenic mice with a hIL-6 receptor antagonist. [electronic resource]
Producer: 20010621Description: 4334-40 p. digitalISSN:- 0022-1767
- Amino Acid Substitution -- genetics
- Animals
- Animals, Newborn -- genetics
- Antibody Formation -- genetics
- Down-Regulation -- genetics
- Female
- Growth Disorders -- genetics
- Humans
- Immunity, Maternally-Acquired
- Immunization, Secondary
- Insulin-Like Growth Factor I -- metabolism
- Interleukin-6 -- administration & dosage
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic -- immunology
- Phosphopyruvate Hydratase -- genetics
- Receptors, Interleukin-6 -- antagonists & inhibitors
- Recombinant Proteins -- administration & dosage
- Vaccination -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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