Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors. [electronic resource]
Producer: 20010510Description: 551-62 p. digitalISSN:- 0022-1007
- Alanine -- genetics
- Amino Acid Substitution
- Antigen Presentation -- immunology
- Binding Sites -- immunology
- Cell Line
- Circular Dichroism
- Gene Products, tax -- immunology
- HLA-A2 Antigen -- genetics
- Humans
- Lymphocyte Activation -- immunology
- Models, Molecular
- Mutagenesis, Site-Directed
- Protein Binding -- genetics
- Protein Structure, Secondary -- physiology
- Receptors, Antigen, T-Cell -- immunology
- Temperature
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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