In utero transplantation of fetal liver cells in the mucopolysaccharidosis type VII mouse results in low-level chimerism, but overexpression of beta-glucuronidase can delay onset of clinical signs. [electronic resource]
Producer: 20010426Description: 1625-34 p. digitalISSN:- 0006-4971
- Animals
- Cell Culture Techniques -- methods
- Fetal Diseases -- therapy
- Fetal Tissue Transplantation -- methods
- Genetic Therapy -- methods
- Glucuronidase -- genetics
- Humans
- Liver -- cytology
- Mice
- Models, Animal
- Mucopolysaccharidosis VII -- therapy
- Transduction, Genetic
- Transplantation Chimera
- Transplantation, Homologous -- methods
- Transplantation, Isogeneic -- methods
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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