Differential p53-dependent mechanism of radiosensitization in vitro and in vivo by the protein kinase C-specific inhibitor PKC412. [electronic resource]
Producer: 20010222Description: 732-8 p. digitalISSN:- 0008-5472
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Combined Modality Therapy
- Dose-Response Relationship, Drug
- Dose-Response Relationship, Radiation
- Enzyme Inhibitors -- pharmacology
- Genotype
- Humans
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Neoplasms, Experimental -- drug therapy
- Protein Kinase C -- antagonists & inhibitors
- Staurosporine -- analogs & derivatives
- Tumor Cells, Cultured -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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