Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal. [electronic resource]
Producer: 20010222Description: 565-9 p. digitalISSN:- 0008-5472
- Adenomatous Polyposis Coli Protein
- Animals
- Apoptosis
- Cell Differentiation -- genetics
- Cell Division -- genetics
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- genetics
- Cytoskeletal Proteins -- genetics
- Diet -- adverse effects
- Female
- Gastrointestinal Neoplasms -- etiology
- Gene Silencing
- Genotype
- Immunohistochemistry
- Intestinal Mucosa -- chemistry
- Male
- Mice
- Mice, Mutant Strains
- Mucins -- analysis
- Mutation
- Proliferating Cell Nuclear Antigen -- analysis
- Survival Analysis
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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