Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue. [electronic resource]
Producer: 20010510Description: 219-22 p. digitalISSN:- 0960-894X
- Amino Acid Motifs
- Aminocaproates -- chemistry
- Antiviral Agents -- chemical synthesis
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Combinatorial Chemistry Techniques
- Drug Design
- Drug Resistance
- HIV Protease Inhibitors -- chemical synthesis
- Immunodeficiency Virus, Feline -- enzymology
- Inhibitory Concentration 50
- Molecular Conformation
- Molecular Mimicry
- Peptides, Cyclic -- chemical synthesis
- Protease Inhibitors -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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