The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination. [electronic resource]
Producer: 20010322Description: 6306-16 p. digitalISSN:- 0950-9232
- Animals
- COS Cells
- Cell Division
- Cell Line, Transformed
- Cysteine Endopeptidases
- Cysteine Proteinase Inhibitors -- pharmacology
- Fibroblasts -- cytology
- Gene Expression
- Genes, Tumor Suppressor
- Glycoproteins -- pharmacology
- Multienzyme Complexes -- antagonists & inhibitors
- Proteasome Endopeptidase Complex
- Proteins -- genetics
- Rats
- Repressor Proteins -- genetics
- Transfection
- Tuberous Sclerosis Complex 1 Protein
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins
- Ubiquitins -- metabolism
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Publication Type: Journal Article
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