The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. [electronic resource]
Producer: 20010322Description: 1389-99 p. digitalISSN:- 1097-2765
- Abnormalities, Multiple -- genetics
- Animals
- Apoptosis -- drug effects
- Brain -- abnormalities
- Cells, Cultured
- Crosses, Genetic
- Embryonic and Fetal Development -- genetics
- Etoposide -- pharmacology
- Female
- Gene Deletion
- Gene Targeting
- Genes, Essential -- genetics
- Hematopoietic Stem Cells -- metabolism
- Histocytochemistry
- Kidney -- abnormalities
- Lymphoid Tissue -- abnormalities
- Male
- Membrane Proteins -- genetics
- Mice
- Mice, Knockout
- Phenotype
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Spleen -- abnormalities
- Thymus Gland -- abnormalities
- bcl-2 Homologous Antagonist-Killer Protein
- bcl-2-Associated X Protein
- fas Receptor -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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