Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent. [electronic resource]
Producer: 20010419Description: 2531-9 p. digitalISSN:- 0022-1767
- Animals
- Autoantigens -- immunology
- B7-1 Antigen -- biosynthesis
- CD28 Antigens -- physiology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Movement -- genetics
- Diabetes Mellitus, Experimental -- genetics
- Drug Administration Schedule
- Epitopes, T-Lymphocyte -- immunology
- Female
- Injections, Intraperitoneal
- Insulin -- biosynthesis
- Interferon-gamma -- metabolism
- Islets of Langerhans -- immunology
- Lymphocyte Activation -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Promoter Regions, Genetic -- immunology
- Rats
- Streptozocin -- administration & dosage
- T-Lymphocyte Subsets -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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