15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. [electronic resource]
Producer: 20010222Description: 6846-50 p. digitalISSN:- 0008-5472
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Antineoplastic Agents -- pharmacology
- Antioxidants -- pharmacology
- Antithrombins -- pharmacology
- Apoptosis -- drug effects
- Arachidonate 15-Lipoxygenase -- pharmacology
- Arachidonic Acid -- pharmacology
- Blotting, Western
- Caffeic Acids -- pharmacology
- Cell Line
- Colonic Neoplasms -- enzymology
- Cyclooxygenase 1
- Cyclooxygenase 2
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors -- pharmacology
- Humans
- Hydroxyeicosatetraenoic Acids -- biosynthesis
- Isoenzymes -- metabolism
- Linoleic Acid -- pharmacology
- Linoleic Acids -- pharmacology
- Membrane Proteins
- Nitrobenzenes -- pharmacology
- Prostaglandin-Endoperoxide Synthases -- metabolism
- Recombinant Proteins -- metabolism
- Sulfonamides -- pharmacology
- Sulindac -- analogs & derivatives
- Time Factors
- Tumor Cells, Cultured
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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