Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells. [electronic resource]
Producer: 20010111Description: 6656-62 p. digitalISSN:- 0008-5472
- Adenocarcinoma -- drug therapy
- Animals
- Antineoplastic Agents -- pharmacokinetics
- Biotransformation
- Cell Division -- drug effects
- Cell Line
- Cysteamine -- analogs & derivatives
- Fibrosarcoma -- drug therapy
- Gliosarcoma -- drug therapy
- Humans
- Kidney -- cytology
- Melanins -- biosynthesis
- Monophenol Monooxygenase -- genetics
- Mutation
- Phenols -- pharmacokinetics
- Prodrugs -- pharmacokinetics
- Propanols -- pharmacokinetics
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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