Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programs. [electronic resource]
Producer: 20010118Description: 61-72 p. digitalISSN:- 0270-7306
- Active Transport, Cell Nucleus
- Animals
- Apoptosis
- Cell Line
- Cysteine Endopeptidases -- metabolism
- DNA -- genetics
- DNA-Binding Proteins -- metabolism
- Encephalomyocarditis virus -- genetics
- Endoribonucleases -- deficiency
- Gene Deletion
- Gene Expression Regulation
- I-kappa B Proteins
- Interferon-beta -- genetics
- Interleukin-6 -- genetics
- Mice
- Multienzyme Complexes -- metabolism
- NF-kappa B -- metabolism
- Phosphorylation
- Proteasome Endopeptidase Complex
- Protein Processing, Post-Translational
- RNA, Double-Stranded -- metabolism
- RNA, Messenger -- genetics
- RNA, Viral -- metabolism
- Tumor Necrosis Factor-alpha -- genetics
- Ubiquitins -- metabolism
- eIF-2 Kinase -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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