Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms. [electronic resource]
Producer: 20010510Description: 10083-96 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Animals
- Arachidonic Acid -- metabolism
- Cell Line
- Cell Membrane -- metabolism
- Dinoprostone -- metabolism
- Electrophoresis, Polyacrylamide Gel
- Group II Phospholipases A2
- Group V Phospholipases A2
- Heparan Sulfate Proteoglycans -- metabolism
- Heparin -- metabolism
- Humans
- Hydrogen-Ion Concentration
- Hydrolysis
- Immunohistochemistry
- Leukotriene C4 -- metabolism
- Mast Cells -- metabolism
- Mast-Cell Sarcoma -- metabolism
- Mice
- Microscopy, Confocal
- Models, Biological
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phospholipases A -- metabolism
- Phosphorylation
- Platelet Activating Factor -- metabolism
- Protein Binding
- RNA -- metabolism
- Rats
- Recombinant Proteins -- metabolism
- Sequence Homology, Amino Acid
- Time Factors
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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