delta-, but not mu- and kappa-, opioid receptor activation protects neocortical neurons from glutamate-induced excitotoxic injury. [electronic resource]
Producer: 20010301Description: 143-53 p. digitalISSN:- 0006-8993
- 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer -- pharmacology
- Analgesics, Non-Narcotic -- pharmacology
- Analgesics, Opioid -- pharmacology
- Animals
- Cells, Cultured
- Cytoprotection -- drug effects
- Embryo, Mammalian
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)- -- pharmacology
- Enkephalin, Leucine-2-Alanine -- pharmacology
- Excitatory Amino Acid Agonists -- pharmacology
- Female
- Glutamic Acid -- pharmacology
- L-Lactate Dehydrogenase -- drug effects
- Naltrexone -- analogs & derivatives
- Narcotic Antagonists -- pharmacology
- Neocortex
- Neurons -- drug effects
- Pregnancy
- Rats
- Rats, Sprague-Dawley
- Receptors, Opioid, delta -- drug effects
- Receptors, Opioid, kappa -- drug effects
- Receptors, Opioid, mu -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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