Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. [electronic resource]
Producer: 20010111Description: 9247-61 p. digitalISSN:- 0270-7306
- 3T3 Cells
- Animals
- CHO Cells
- Cell Membrane -- metabolism
- Chemotaxis -- drug effects
- Cricetinae
- DNA-Binding Proteins -- metabolism
- Humans
- I-kappa B Proteins
- Immediate-Early Proteins -- metabolism
- Insulin-Like Growth Factor I -- pharmacology
- Lysophospholipids
- Mice
- NF-KappaB Inhibitor alpha
- Phosphatidylinositol 3-Kinases -- metabolism
- Protein Isoforms -- metabolism
- Protein Kinase Inhibitors
- Protein Serine-Threonine Kinases -- metabolism
- Receptors, Cell Surface -- metabolism
- Receptors, G-Protein-Coupled
- Receptors, Lysophospholipid
- Recombinant Proteins -- genetics
- Signal Transduction
- Sphingosine -- analogs & derivatives
- Stress Fibers -- metabolism
- Transfection
- cdc42 GTP-Binding Protein -- metabolism
- p21-Activated Kinases
- rac GTP-Binding Proteins -- antagonists & inhibitors
- rho GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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