Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level. [electronic resource]
Producer: 20001214Description: 41-54 p. digitalISSN:- 1056-8719
- Alkaline Phosphatase -- metabolism
- Animals
- Antibodies -- pharmacology
- Aryl Hydrocarbon Hydroxylases
- Carbon Monoxide -- metabolism
- Catalysis
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dexamethasone -- pharmacology
- Enzyme Induction -- drug effects
- Enzyme Inhibitors -- pharmacology
- Epithelial Cells -- enzymology
- Female
- Gene Expression Regulation, Enzymologic
- Glycerol -- pharmacology
- Hydroxylation -- drug effects
- Hypnotics and Sedatives -- metabolism
- Intestines -- cytology
- Ketoconazole -- pharmacology
- Liver -- enzymology
- Male
- Microsomes -- enzymology
- Midazolam -- metabolism
- Oxidoreductases, N-Demethylating -- antagonists & inhibitors
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Sprague-Dawley
- Reproducibility of Results
- Troleandomycin -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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