Prostaglandin E2 selectively enhances the IgE-mediated production of IL-6 and granulocyte-macrophage colony-stimulating factor by mast cells through an EP1/EP3-dependent mechanism. [electronic resource]
Producer: 20010111Description: 6545-52 p. digitalISSN:- 0022-1767
- Adjuvants, Immunologic -- physiology
- Animals
- Bone Marrow Cells -- immunology
- Cell Degranulation -- immunology
- Cell Line
- Cyclic AMP -- physiology
- Cytokines -- biosynthesis
- Dinoprostone -- physiology
- Drug Synergism
- Granulocyte-Macrophage Colony-Stimulating Factor -- biosynthesis
- Immunoglobulin E -- physiology
- Interleukin-6 -- biosynthesis
- Kinetics
- Mast Cells -- immunology
- Mice
- Mice, Inbred C57BL
- Protein Isoforms -- biosynthesis
- Receptors, Prostaglandin E -- biosynthesis
- Receptors, Prostaglandin E, EP1 Subtype
- Receptors, Prostaglandin E, EP3 Subtype
- Second Messenger Systems -- physiology
- Up-Regulation -- immunology
- beta-N-Acetylhexosaminidases -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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