Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97). [electronic resource]
Producer: 20001220Description: 912-26 p. digitalISSN:- 0022-3565
- Animals
- Anti-Asthmatic Agents -- pharmacokinetics
- Arachidonate 5-Lipoxygenase -- metabolism
- Arachidonic Acid -- metabolism
- Calcimycin -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Eosinophils -- drug effects
- Female
- Janus Kinase 3
- Leukotriene C4 -- biosynthesis
- Male
- Mast Cells -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, SCID
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Quinazolines -- pharmacokinetics
- Receptors, IgE -- physiology
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Publication Type: Journal Article
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