Biodistribution and metabolism of a mixed backbone oligonucleotide (GEM 231) following single and multiple dose administration in mice. [electronic resource]
Producer: 20010222Description: 333-45 p. digitalISSN:- 1087-2906
- Animals
- Autoradiography
- Cyclic AMP-Dependent Protein Kinases -- biosynthesis
- Dose-Response Relationship, Drug
- Electrophoresis, Polyacrylamide Gel
- Injections, Intravenous
- Injections, Subcutaneous
- Kidney -- metabolism
- Liver -- metabolism
- Male
- Mice
- Mice, Inbred Strains
- Neoplasm Transplantation
- Oligodeoxyribonucleotides, Antisense -- administration & dosage
- Sulfur Radioisotopes
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Publication Type: Journal Article
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