Caspases that are activated during generation of nuclear polyglutamine aggregates are necessary for DNA fragmentation but not sufficient for cell death. [electronic resource]
Producer: 20001214Description: 547-56 p. digitalISSN:- 0360-4012
- Apoptosis -- physiology
- Caspase 3
- Caspase 8
- Caspase 9
- Caspases -- metabolism
- Cell Count -- statistics & numerical data
- Cell Nucleus -- metabolism
- DNA Fragmentation -- physiology
- Embryonal Carcinoma Stem Cells
- Humans
- Neoplastic Stem Cells -- cytology
- Neurodegenerative Diseases -- genetics
- Peptides -- metabolism
- Signal Transduction -- genetics
- Trinucleotide Repeat Expansion -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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