Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2). [electronic resource]
Producer: 20001207Description: 739-45 p. digitalISSN:- 1524-4571
- Adenylyl Cyclase Inhibitors
- Adenylyl Cyclases -- metabolism
- Angiogenesis Inhibitors -- pharmacology
- Apoptosis
- Bridged Bicyclo Compounds, Heterocyclic
- Cell Survival
- Clone Cells
- Colforsin -- pharmacology
- Cyclic AMP -- metabolism
- Endothelium, Vascular -- cytology
- Enzyme Activation
- Fatty Acids, Unsaturated
- Humans
- Hydrazines -- pharmacology
- Isoquinolines -- pharmacology
- Phosphorylation -- drug effects
- Protein Isoforms -- antagonists & inhibitors
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-akt
- Receptors, Thromboxane -- antagonists & inhibitors
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Sulfonamides
- Thromboxane A2 -- antagonists & inhibitors
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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