PKA site mutations of ROMK2 channels shift the pH dependence to more alkaline values. [electronic resource]
Producer: 20001207Description: F919-26 p. digitalISSN:- 1931-857X
- Acid-Base Equilibrium -- genetics
- Alkalies -- metabolism
- Animals
- Binding Sites -- genetics
- Butyric Acid -- metabolism
- Cells, Cultured
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Hydrogen-Ion Concentration -- drug effects
- Membrane Potentials -- drug effects
- Mutagenesis, Site-Directed
- Oocytes -- cytology
- Patch-Clamp Techniques
- Phosphorylation -- drug effects
- Potassium Channels -- genetics
- Potassium Channels, Inwardly Rectifying
- Rats
- Structure-Activity Relationship
- Xenopus laevis
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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