Total synthesis and antitumor activity of 12,13-desoxyepothilone F: an unexpected solvolysis problem at C15, mediated by remote substitution at C21. [electronic resource]
Producer: 20001128Description: 6525-33 p. digitalISSN:- 0022-3263
- Animals
- Antineoplastic Agents -- chemical synthesis
- Antineoplastic Agents, Phytogenic -- pharmacology
- Drug Screening Assays, Antitumor
- Epothilones
- Humans
- Lactones -- chemical synthesis
- Mice
- Mice, Nude
- Paclitaxel -- pharmacology
- Thiazoles -- chemical synthesis
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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