M1 muscarinic receptors block caspase activation by phosphoinositide 3-kinase- and MAPK/ERK-independent pathways. [electronic resource]
Producer: 20001114Description: 825-33 p. digitalISSN:- 1350-9047
- Animals
- Apoptosis
- Atropine -- pharmacology
- Caspase Inhibitors
- Caspases -- biosynthesis
- Cell Extracts
- Culture Media, Serum-Free
- Dose-Response Relationship, Drug
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- MAP Kinase Signaling System
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Muscarinic Agonists -- pharmacology
- Muscarinic Antagonists -- pharmacology
- Oxotremorine -- pharmacology
- PC12 Cells
- Peptide Hydrolases -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Rats
- Receptor, Muscarinic M1
- Receptors, Muscarinic -- metabolism
- Signal Transduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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