Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates. [electronic resource]
Producer: 20010105Description: 773-91 p. digitalISSN:- 1074-5521
- Alanine -- analogs & derivatives
- Antineoplastic Agents -- chemical synthesis
- Arylsulfatases -- antagonists & inhibitors
- Binding Sites
- Breast Neoplasms -- drug therapy
- Coumarins -- chemical synthesis
- Dehydroepiandrosterone Sulfate -- metabolism
- Dose-Response Relationship, Drug
- Estrone -- analogs & derivatives
- Female
- Glycine -- analogs & derivatives
- Heterocyclic Compounds, 3-Ring -- chemical synthesis
- Humans
- Hydrogen Bonding
- Kinetics
- Microsomes -- drug effects
- Models, Molecular
- Placenta -- drug effects
- Postmenopause -- metabolism
- Steryl-Sulfatase
- Structure-Activity Relationship
- Sulfatases -- antagonists & inhibitors
- Sulfonamides -- chemical synthesis
- Sulfonic Acids
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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