Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. [electronic resource]
Producer: 20010201Description: 1109-20 p. digitalISSN:- 0091-2700
- Adolescent
- Adult
- Bleeding Time
- Cyclooxygenase 1
- Cyclooxygenase 2
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors -- adverse effects
- Diclofenac -- adverse effects
- Dinoprostone -- metabolism
- Female
- Humans
- Ibuprofen -- adverse effects
- Isoenzymes -- antagonists & inhibitors
- Lactones -- adverse effects
- Lipopolysaccharides -- pharmacology
- Meloxicam
- Membrane Proteins
- Middle Aged
- Naproxen -- adverse effects
- Platelet Aggregation -- drug effects
- Prostaglandin-Endoperoxide Synthases -- metabolism
- Prostaglandins -- urine
- Sulfones
- Thiazines -- adverse effects
- Thiazoles -- adverse effects
- Thromboxane B2 -- blood
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Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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