Pepstatin A-sensitive aspartic proteases in lysosome are involved in degradation of the invariant chain and antigen-processing in antigen presenting cells of mice infected with Leishmania major. [electronic resource]
Producer: 20001027Description: 693-701 p. digitalISSN:- 0006-291X
- Animals
- Antibody Formation -- drug effects
- Antigen Presentation -- immunology
- Antigen-Presenting Cells -- immunology
- Antigens, Differentiation, B-Lymphocyte -- immunology
- Antigens, Protozoan -- metabolism
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- CD4-Positive T-Lymphocytes -- drug effects
- Cathepsin B -- antagonists & inhibitors
- Cell Division -- drug effects
- Cysteine Proteinase Inhibitors -- therapeutic use
- Cytokines -- metabolism
- Dipeptides -- therapeutic use
- Disease Models, Animal
- Female
- Histocompatibility Antigens Class II -- immunology
- Leishmania major
- Leishmaniasis, Cutaneous -- drug therapy
- Lymphocytes -- drug effects
- Lysosomes -- metabolism
- Mice
- Mice, Inbred BALB C
- Mice, Inbred DBA
- Pepstatins -- pharmacology
- Th1 Cells -- drug effects
- Th2 Cells -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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