Cathepsin-B fusion proteins misroute secretory protein partners such as the proprotein convertase PC2-7B2 complex toward the lysosomal degradation pathways. [electronic resource]
Producer: 20001027Description: 594-9 p. digitalISSN:- 0006-291X
- Ammonium Chloride -- pharmacology
- Animals
- Cathepsin B -- antagonists & inhibitors
- Cells, Cultured
- Cysteine Proteinase Inhibitors -- pharmacology
- Dipeptides -- pharmacology
- Lysosomes -- drug effects
- Mice
- Nerve Tissue Proteins -- genetics
- Neuroendocrine Secretory Protein 7B2
- Pituitary Hormones -- genetics
- Proprotein Convertase 2
- Recombinant Fusion Proteins -- metabolism
- Subtilisins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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