The CD4-mediated immune response is critical in determining the outcome of infection using Theiler's viruses with VP1 capsid protein point mutations. [electronic resource]
Producer: 20001031Description: 9-19 p. digitalISSN:- 0042-6822
- Amino Acid Substitution -- genetics
- Animals
- Antibodies, Viral -- immunology
- CD4 Antigens -- genetics
- CD4-Positive T-Lymphocytes -- immunology
- CD8 Antigens -- genetics
- CD8-Positive T-Lymphocytes -- immunology
- Capsid -- genetics
- Capsid Proteins
- Cardiovirus Infections -- immunology
- Cell Line
- Central Nervous System -- immunology
- Cytotoxicity, Immunologic
- Disease Models, Animal
- Female
- Histocompatibility Antigens Class II -- immunology
- In Situ Hybridization
- Mice
- Mice, Inbred Strains
- Mice, Knockout
- Multiple Sclerosis -- immunology
- Neutralization Tests
- Point Mutation -- genetics
- RNA, Viral -- analysis
- Receptor, Interferon alpha-beta
- Receptors, Interferon -- genetics
- Theilovirus -- genetics
- Virulence
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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