Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action. [electronic resource]
Producer: 20001024Description: 5325-31 p. digitalISSN:- 0021-9193
- Acetamides -- chemistry
- Amino Acid Substitution
- Anti-Bacterial Agents -- chemistry
- Base Sequence
- Binding Sites
- Catalysis
- Catalytic Domain
- Drug Resistance, Microbial
- Escherichia coli -- drug effects
- Genes, Bacterial
- Genetic Engineering
- Linezolid
- Molecular Sequence Data
- Molecular Structure
- Mutagenesis
- Nucleic Acid Conformation
- Oxazolidinones -- chemistry
- Peptidyl Transferases -- metabolism
- RNA, Bacterial -- chemistry
- RNA, Ribosomal, 23S -- chemistry
- Ribosomes
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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