The B subunit of Shiga toxin fused to a tumor antigen elicits CTL and targets dendritic cells to allow MHC class I-restricted presentation of peptides derived from exogenous antigens. [electronic resource]
Producer: 20001010Description: 3301-8 p. digitalISSN:- 0022-1767
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP-Binding Cassette Transporters -- genetics
- Acetylcysteine -- analogs & derivatives
- Animals
- Antigen Presentation -- drug effects
- Antigens, Neoplasm -- administration & dosage
- Bacterial Toxins -- administration & dosage
- Brefeldin A -- pharmacology
- Cytotoxicity, Immunologic -- genetics
- Dendritic Cells -- immunology
- Female
- Histocompatibility Antigens Class I -- immunology
- Injections, Intraperitoneal
- Intracellular Fluid -- immunology
- Leukemia L1210
- Lymphocyte Activation -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Knockout
- Ovalbumin -- administration & dosage
- Peptides -- immunology
- Protein Processing, Post-Translational -- drug effects
- Recombinant Fusion Proteins -- administration & dosage
- Sarcoma, Experimental -- genetics
- Shiga Toxins
- Signal Transduction -- genetics
- T-Lymphocytes, Cytotoxic -- immunology
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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