Basic fibroblast growth factor utilizes both types of component subunits of Gs for dual signaling in human adipocytes. Stimulation of adenylyl cyclase via Galph(s) and inhibition of NADPH oxidase by Gbeta gamma(s). [electronic resource]
Producer: 20001229Description: 35920-5 p. digitalISSN:- 0021-9258
- Adenylyl Cyclase Inhibitors
- Adenylyl Cyclases -- metabolism
- Adipocytes -- drug effects
- Antibodies -- pharmacology
- Cell Membrane -- drug effects
- Cyclic AMP-Dependent Protein Kinases -- pharmacology
- Fibroblast Growth Factor 1 -- pharmacology
- Fibroblast Growth Factor 2 -- pharmacology
- GTP-Binding Protein alpha Subunits, Gs -- antagonists & inhibitors
- Guanosine 5'-O-(3-Thiotriphosphate) -- pharmacology
- Humans
- Hydrogen Peroxide -- metabolism
- Insulin -- pharmacology
- NADPH Oxidases -- antagonists & inhibitors
- Peptide Fragments -- pharmacology
- Receptor Protein-Tyrosine Kinases -- metabolism
- Recombinant Proteins
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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