RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells. [electronic resource]
Producer: 20000926Description: 44-52 p. digitalISSN:- 0020-7136
- Antibodies, Monoclonal -- immunology
- Antibody Specificity
- Breast -- enzymology
- Cell Line, Transformed
- Cell Transformation, Neoplastic -- genetics
- Cells, Cultured
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Epidermal Growth Factor -- metabolism
- ErbB Receptors -- genetics
- Female
- Gene Expression Regulation
- Genes, ras -- genetics
- Growth Inhibitors -- pharmacology
- Humans
- MAP Kinase Signaling System -- physiology
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Phosphorylation
- Point Mutation
- Proto-Oncogene Proteins c-raf -- genetics
- Proto-Oncogene Proteins p21(ras) -- genetics
- Subcellular Fractions -- enzymology
- Substrate Specificity
- Transfection
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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