Differential effects of the mixed ET(A)/ET(B)-receptor antagonist bosentan on endothelin-induced bronchoconstriction, vasoconstriction and prostacyclin release. [electronic resource]
Producer: 20010202Description: 128-36 p. digitalISSN:- 0028-1298
- Animals
- Antihypertensive Agents -- pharmacology
- Area Under Curve
- Bosentan
- Bronchoconstriction -- drug effects
- Endothelin Receptor Antagonists
- Endothelin-1 -- metabolism
- Endothelin-3 -- pharmacology
- Endothelins -- antagonists & inhibitors
- Epoprostenol -- metabolism
- Female
- Image Processing, Computer-Assisted
- In Vitro Techniques
- Lung -- metabolism
- Peptide Fragments -- pharmacology
- Rats
- Rats, Wistar
- Receptor, Endothelin A
- Receptor, Endothelin B
- Respiratory Mechanics -- drug effects
- Sulfonamides -- pharmacology
- Vasoconstriction -- drug effects
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Publication Type: Journal Article
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