F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation. [electronic resource]
Producer: 20000831Description: 3858-65 p. digitalISSN:- 0950-9232
- Acetylcysteine -- analogs & derivatives
- Animals
- Apoptosis -- drug effects
- CDC2-CDC28 Kinases
- Carcinoma, Embryonal -- pathology
- Cell Cycle -- physiology
- Cyclin B -- metabolism
- Cyclin B1
- Cyclin D1 -- metabolism
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinases -- metabolism
- Cyclins -- genetics
- Cysteine Endopeptidases -- drug effects
- Cysteine Proteinase Inhibitors -- pharmacology
- DNA Damage -- radiation effects
- G1 Phase -- radiation effects
- Gamma Rays
- Mice
- Multienzyme Complexes -- drug effects
- Nocodazole -- pharmacology
- Promoter Regions, Genetic
- Proteasome Endopeptidase Complex
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins
- S Phase -- radiation effects
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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