Role of TNF-alpha in high-dose antigen therapy in experimental autoimmune neuritis: inhibition of TNF-alpha by neutralizing antibodies reduces T-cell apoptosis and prevents liver necrosis. [electronic resource]
Producer: 20000719Description: 368-76 p. digitalISSN:- 0022-3069
- Animals
- Antigens -- administration & dosage
- Apoptosis -- drug effects
- Cell Line
- Chemical and Drug Induced Liver Injury
- Dose-Response Relationship, Drug
- Female
- Humans
- Liver -- pathology
- Liver Diseases -- prevention & control
- Myelin P2 Protein -- adverse effects
- Necrosis
- Neuritis, Autoimmune, Experimental -- drug therapy
- Rats
- Rats, Inbred Lew
- Recombinant Proteins -- adverse effects
- Sciatic Nerve -- pathology
- T-Lymphocytes -- metabolism
- Tumor Necrosis Factor-alpha -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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