Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1. [electronic resource]
Producer: 20000908Description: 397-405 p. digitalISSN:- 0269-2139
- Amino Acid Substitution -- genetics
- Aminobiphenyl Compounds -- pharmacology
- Binding Sites -- genetics
- Crystallography, X-Ray
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Gelatin -- chemistry
- HeLa Cells
- Humans
- Matrix Metalloproteinase 3 -- biosynthesis
- Matrix Metalloproteinase Inhibitors
- Models, Molecular
- Mutagenesis, Site-Directed
- Protein Binding -- physiology
- Protein Structure, Tertiary
- Structure-Activity Relationship
- Tissue Inhibitor of Metalloproteinase-1 -- chemistry
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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