Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes. [electronic resource]
Producer: 20000727Description: 333-41 p. digitalISSN:- 0006-291X
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- analysis
- ATP-Binding Cassette Transporters -- analysis
- Aryl Hydrocarbon Hydroxylases
- Blotting, Western
- Cell Size -- drug effects
- Cells, Cultured
- Cytochrome P-450 CYP1A1 -- biosynthesis
- Cytochrome P-450 CYP1A2 -- biosynthesis
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP2C9
- Cytochrome P-450 CYP2E1 -- metabolism
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- analysis
- Enzyme Induction -- drug effects
- Epidermal Growth Factor -- pharmacology
- Hepatocyte Growth Factor -- pharmacology
- Humans
- Isoenzymes -- analysis
- Liver -- cytology
- Methylcholanthrene -- pharmacology
- Mixed Function Oxygenases -- biosynthesis
- Multidrug Resistance-Associated Proteins
- Neoplasm Proteins -- genetics
- Phenobarbital -- pharmacology
- RNA, Messenger -- genetics
- Rifampin -- pharmacology
- Steroid 16-alpha-Hydroxylase
- Steroid Hydroxylases -- metabolism
- Vault Ribonucleoprotein Particles -- genetics
- beta-Naphthoflavone -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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