Molecular characterization of the thermosensitive E1 ubiquitin-activating enzyme cell mutant A31N-ts20. Requirements upon different levels of E1 for the ubiquitination/degradation of the various protein substrates in vivo. [electronic resource]
Producer: 20000817Description: 3712-22 p. digitalISSN:- 0014-2956
- Animals
- Cell Line
- Cysteine Proteinase Inhibitors -- pharmacology
- Enzyme Activation
- Fibroblasts
- Histones -- metabolism
- Hot Temperature
- Leupeptins -- pharmacology
- Ligases -- antagonists & inhibitors
- Mice
- Mutation
- Proto-Oncogene Proteins c-jun -- metabolism
- Temperature
- Tumor Suppressor Protein p53 -- metabolism
- Ubiquitin-Activating Enzymes
- Ubiquitin-Protein Ligases
- Ubiquitins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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