Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins. [electronic resource]
Producer: 20000810Description: 3929-38 p. digitalISSN:- 0006-4971
- Acute Disease
- Adult
- Aged
- Aged, 80 and over
- Apoptosis -- drug effects
- Bone Marrow Cells -- drug effects
- Cell Division -- drug effects
- Cells, Cultured
- Cytarabine -- toxicity
- Female
- Genes, bcl-2
- HL-60 Cells
- Humans
- Leukemia, Myeloid
- Liposomes
- Male
- Middle Aged
- Oligodeoxyribonucleotides, Antisense -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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